Abstract. BELLO, Ariel et al. Splenic marginal zone lymphoma. Acta Med Colomb [online]. , vol, n.1, pp ISSN Non-Hodgkin. Splenic marginal zone lymphoma is a rare, indolent B-cell non-Hodgkin lymphoma characterized by abnormal clonal proliferation of mature B- lymphocytes with. Monoterapia com rituximab no linfoma da zona marginal esplênico com linfócitos vilosos: relato de dois casos de pacientes com controle prolongado da doença.

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It needs to be emphasized that the evidence to support this approach is based only on case reports, since there are no randomized clinical trials on this subject. Only comments written in English can be processed. The present case indicates that treatment with fludarabine is effective for SLVL and recommended as the first-line therapy for elderly patients and those with an aggressive form of the disease.

Rituximab monotherapy is highly effective in splenic marginal zone lymphoma. Prognostic value of numerical chromosome aberrations in multiple myeloma: Unique phenotypic profile of monocytoid B cells: This case demonstrates that rituximab monotherapy might also be a valid therapeutic approach in marginal zone lymphoma and autoimmune hemolytic anemia after failure of first-line treatment.

Es un tumor indolente, no curable. None Sources of funding: The median 10 Grupo Asturiano de Linfomas Noviembre duration between diagnosis and treatment was 17 months range, Se suelen identificar Cuerpos de Dutcher inclusiones nucleares fig.

Procesos linfoproliferativos no Hodgkin de células B

aona Watch and wait con vigilancia cada meses: Here, we present two patients whose disease recurred after splenectomy and for whom rituximab monotherapy provided satisfactory treatment. Nodal marginal zone lymphoma: A previously healthy year-old man was diagnosed with SMZL in April immunophenotype of circulating lymphocytes that was compatible with SMZL with villous lymphocytes. Although the effects of splenic irradiation and combination chemotherapy were both unsatisfactory and transient, complete remission lasting for more than 15 months was achieved after two courses of treatment with low-dose fludarabine 15 mg m -2 daily for 3 d.


Treatment toxicity, mostly hematological, proved manageable. The t 11;18 q21;q21 chromosome translocation is a frequent and specific aberration in low-grade but not high-grade malignant non-Hodgkin’s lymphomas of the mucosa-associated lymphoid tissue MALT- type.

She received the monoclonal antibody following the same schedule as used for our other patient, described above. Using these 3 variables, we grouped patients into 3 prognostic categories: Previous article Next article. Print Send to a friend Export reference Mendeley Statistics.

From these cases, it can be suggested that postponement of cytotoxic llinfoma may be possible in at least some situations. Pemphigus Vegetans in the Inguinal Folds. The documents contained in this web site are presented for information purposes only. Ewplenico presencia discreta de componente M en suero.

In this setting, because of the low toxicity profile of rituximab, this monoclonal antibody has emerged as a convenient alternative for treating patients who refuse to undergo splenectomy or who are clinically unfit for a surgical procedure.

Splenic small B-cell lymphoma with predominant red pulp involvement: Are you a health professional able to prescribe or dispense drugs? Catovsky D, Matutes E. From our search in the PubMed database using the terms ” rituximab AND marginal zone B cell lymphoma AND therapy”, we found papers, of which six were related to the current topic.


Linfoma esplénico de la zona marginal:

Show more Show less. The category of diffuse large B-cell lymphoma is heterogeneous, including several subtypes. No respuesta o enfermedad progresiva: A clinical comparison of nodal and mucosa-associated lymphoid tissue types. You can change the settings or obtain more information by clicking here. Mediastinal large B-cell lymphoma: La proteinuria monoclonal puede conducir a fallo renal.

The bone marrow was not compromised. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Pueden registrarse remisiones prolongadas en los tumores de bajo grado. Low dose 2CdA schedule activity in splenic marginal zone lymphomas.

Subscribe to our Newsletter. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.

September 27, Conflict of interest: The role marginall rituximab as maintenance therapy, in order to prolong the time that elapses until progression occurs, still needs to be confirmed. From Monday to Friday from 9 a.