ASKEP OSTEOSARKOMA PDF

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Osteosarkoma didefinisikan sebagai suatu neoplasma dimana jaringan osteoid disintesis oleh sel ganas. The most frequent type is osteosarcoma in the long bone metaphysis, primary, intramedullary, with high gradation of osteoblasts.

Macroscopically, it manifests as a big, sandy, whitish grey tumor, which is often with bleeding areas and cysts; meanwhile, microscopically it varies.

A teenager with a painful mass around the knee has to undergo further examination for early detection of osteosarcoma. Pada kasus askfp belasan dengan massa yang nyeri di sekitar lutut perlu dilakukan pemeriksaan lanjut untuk deteksi dini osteosarkoma. Most osteosarcoma tumor develop in the distal part of femur in the metaphysis.

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Penyebaran hematogen sering terjadi pada awal penyakit, biasanya ke paru-paru dan tulang. Prognosis penyakit ini dipengaruhi oleh ukuran tumor, derajat nekrosis, penyebaran ke korteks dan jaringan lunak, serta adanya metastasis.

Gambaran makroskopik yaitu tumor besar, berpasir, berwarna abu-abu keputihan, dan sering terdapat area perdarahan dan kiste sedangkan gambaran mikroskopik bervariasi.

Radiological examination is important in early evaluation of osteosarcoma. Gejala awal tidak spesifik yaitu nyeri dengan atau tanpa teraba massa.

Umumnya tumor tumbuh pada distal femur di bagian metafisis. Osteoblas maligna yang memroduksi matriks osteoid merupakan gambaran diagnostik. Early signs and symptoms are not specific, mostly manifests as pain with or without palpable mass.

The causes are still unknown, however, a variety of agents and diseases are related to the development of this disease. User Username Password Remember me.

JURNAL BIOMEDIK

oteosarkoma Pemeriksaan radiologik berperan penting dalam evaluasi awal osteosarkoma. Hematogen metastasis often occurs at the early stage of this disease mostly to lungs and bones.

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Morphologically, there are axkep types of osteosarcoma. The prognosis of such cases depends on the tumor size, necrosis degree, dissemination to cortex and soft tissue, and metastasis.

Penyakit ini termasuk keganasan sistem skeletal nonhematopoetik yang tersering dengan distribusi usia bimodal. Secara morfologik terdapat beberapa jenis osteosarkoma, yang tersering ialah osteosarkoma pada metafisis tulang panjang, primer, intrameduler, dengan osteoblas bergradasi tinggi.

OSTEOSARKOMA | Loho | JURNAL BIOMEDIK

Malignant osteoblasts that produce osteoid matrix is the diagnostic tool. Osteosarkoma is defined as a neoplasma in which the osteoid tissue is synthesized by malignant cells. Penyebab osteosarkoma tidak diketahui, namun berbagai agen dan status penyakit dihubungkan dengan perkembangan penyakit ini.

It belongs to the most frequent nonhemapoietic skeletal malignancy with a bimodal age distribution.