Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional. Mandible / maxilla – Benign tumors / tumor-like conditions: adenomatoid odontogenic tumor.

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Peripheral type Peripheral AOT occurring far distant from tooth germ structures is rarely encountered. Atypical case of periapical adenomatoid odontogenic tumour. Malignant transformation in craniopharyngiomas, although rare, does occur.

World Health Organization, Introduction Dreibaldt in was the first to describe adenomatoid odontogenic tumor AOTwhich is an uncommon benign epithelial lesion of odontogenic origin known as a pseudo-adenoameloblastoma [ 1 ].

Surgical exposure of the defect Click here to view. The follicular variant is diagnosed earlier in life mean age, 17 years compared to the extrafollicular variant mean age, 24 years odontogehic, whereas Bull Tokyo Dent Coll ; A, E Follicular type. Related articles Adenomatoid odontogenic tumour extra follicular impacted canine.

These features are common in giant cell tumors, aneurysmal bone cysts, and renal cell carcinoma metastasis, thus a definitive diagnosis can be made through histopathology. However, they contain fine calcifications snowflakea feature that may be helpful in differentiating an Odonyogenic from dentigerious cyst.

Calcifying cystic odontogenic tumor and adenomatoid odontogenic tumor: Rho GTPases that regulate the cell cycle, shape, polarization, invasion, migration, and apoptosis are overexpressed in ameloblastomas. Adenomatoid odontogenic tumor associated with dentigerous cyst in posterior maxilla: Int J Oral Maxillofac Surg ; Ameloblastoma arising in odontogenic tumorw The growth was slow over 18 months, which favors an early enucleation. Clinically, these lesions cannot be differentiated from the common gingival fibrous lesion [ 34 ].

The tumor was well encapsulated, and the lateral incisor was easily removed with the lesion Figure 4. Ameloblastoma of the jaws: The purpose of this article is to report and analyze four unusual cases of Adenmoatoid located in the mandible, with an emphasis on radiographic findings adsnomatoid with pathologic correlation, and to review the existing literature on this tumor. Bernier and Tiecke were the first to publish a case using the name adeno ameloblastoma.


Permanent incisors, premolars, molars, and deciduous teeth are rarely involved [ 810 ]. A surgical exposition wdenomatoid the crown and bonding of a bracket on the maxillary left lateral incisor were also planned a coronoplasty of the first premolar to a canine shape.

Case Reports in Dentistry

Follicular type The follicular type of ameloblastoma frequently forms various sizes of dental follicle structures and possesses an outer arrangement of columnar or palisaded ameloblast-like cells and inner zone of triangular-shaped cells resembling the stellate reticulum in the bell stage of the tooth germ Fig.

This feature may help to distinguish an AOT from a dentigerous cyst [ 3910 ]. Adenomatoid odontogenic cyst, adenomatoid odontogenic tumor, hamartoma. Adenomatoid odontogenic tumor AOT is a rare odontogenic tumour oontogenic is frequently misdiagnosed as odontogenic cyst. These expression patterns of matrix proteins agree with the more locally invasive behavior of ameloblastomas in comparison to AOTs.

Pathological analysis of the basal cell carcinoma. Between the epithelial cells as well as in the center of rosette-like structures is amorphous eosinophilia material.

Adenomatoid odontogenic tumor – Wikipedia

Therefore, odpntogenic with numerous radiopaque foci particularly when the radiolucency surrounds a portion of the root or entire tooth is suggestive of an AOT rather than a calcifying cystic odontogenic tumor.

Acanthomatous ameloblastoma masquerading as a squamous cell carcinoma.

AOT usually surrounds an unerupted tooth, and it looks as a corticated adeonmatoid with small radiopacities, but there are cases where the lesion has no radiopaque component, and in such cases, a dentigerous cyst is the preferred differential diagnosis. Case report and review of the literature.

Mandibular adenomatoid odontogenic tumor: Radiographic and pathologic correlation

Ameloblastin expression in rat incisors and human tooth germs. All the variants of AOT exhibit identical histologic features. Odontogenic Tumor facts and figures.


AOTs frequently resemble other odontogenic lesions such as dentigerous cysts or ameloblastomas. It is seen more frequently in female than in male patients. Kumar, Vijayasamundeeswari, and S. The epithelial cells may form rosette-like structures around a central space, which may be empty or contain a small amount of eosinophilic material Figure 5. Expression of extracellular matrix proteins in ameloblastomas and adenomatoid odontogenic tumors.

Malignancies in ameloblastomas may involve local dysplastic change or metastasis in the tissue. The history revealed an orthodontic treatment started in December with a treatment plan involving extraction of tmuors 34, 44, 23, and New author database being installed, click here for details. B, F Whirling epithelial cells with adenomatoid structures. Hemangiomatous ameloblastoma in maxilla: The histopathologic examination confirmed the diagnosis of a follicular AOT adenomaoid.

Here we report a case of adenomatoid odontogenic tumor AOT in the maxilla in a young girl aged 14 years and its surgical management.

In this case, AOT was associated with the lateral maxillary incisor. It should be differentially diagnosed from a dentigerous cyst and the main difference is that the radiolucency in case of AOT extends apically beyond the cementoenamel junction.

Adenomatoid odontogenic tumor, an uncommon tumor

The tumor is well encapsulated and covered the entire crown and overlapped the root of the lateral incisor. This implies that AOT has less aggressive behavior than ameloblastomas.

A comparative immunohistochemical study of Ki and Bcl-2 expression in solid ameloblastoma and adenomatoid odontogenic tumor. Since this tumor shows considerable clinical and radiographical similarities with a dentigerous cyst, a differential diagnosis is necessary.